Fish oils in the prevention of atherosclerosis
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Date
1992
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Abstract
The hypothesis that oils derived from the flesh of fish and marine mammals inhibit the atherosclerotic process is critically reviewed. Populations consuming a diet rich in fish have low rates of coronary heart disease. Dietary fish oil is associated with changes in serum lipids, prostaglandin and leukotriene metabolism, enhanced endothelial function and effects on growth factors released from platelets, leukocytes and endothelial cells. Dietary fish oil supplementation has been associated with inhibition of atherosclerosis experimentally induced by dietary hyperlinidemia and balloon injury. Results of studies of the use of fish oil to inhibit postangioplasty restenosis in human subjects have bees inconclusive.
Description
Journal of the American College of Cardiology
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Citation
10.1016/0735-1097(92)90070-4