Browsing by Author "Brown BJ"

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    Pattern of childhood cancer in University College Hospital, Ibadan
    (2014) Babatunde TO; Akang EE; Ogun GO; Brown BJ
    Background Cancer is an important cause of morbidity and mortality among children under 15 years old worldwide. Aim: To describe the pattern of childhood cancer in Ibadan. Methods Histologically and cytologically confirmed cases of cancer in children aged <15 years diagnosed at the University College Hospital (UCH), Ibadan, between January 1991 and December 2010 were recruited. The cases were categorised using the International Classification of Childhood Cancer, third edition (ICCC-3). Results There were 625 cases, comprising 360 (57.6%) males with a modal age of 3 years. The most common neoplasms were lymphomas (22.4%). Other common neoplasms were retinoblastomas (21%), soft tissue sarcomas (14.9%), leukaemias (10.2%) and CNS tumours (6.9%). Lymphomas, bone tumours, malignant hepatic tumours and other malignant epithelial neoplasms had the highest mean and modal ages, while retinoblastomas, neuroblastomas, germ cell tumours and renal tumours had the lowest mean and modal ages. Conclusion There has been a decline in the frequency of childhood cancer cases at UCH, Ibadan, in the last 20 years. This may be due to establishment of additional specialist centres in the subregion. Retinoblastoma is now the most common individual childhood cancer at Ibadan, due to a persistent decline in the frequency of Burkitt lymphoma.